I've read all the resources, but I'm still a little lost.  

Hey guys, so I've got an Asus X550, I've got a USB to PCI riser on order

https://www.ebay.com/itm/222367957172    Do these actually work? They were recommended on here.

and an R9 380 GPU, and a power supply.
What I know so far is that I pull out my laptop's wifi card and use the mini pci port there. I then plug everything in, that's when I'm unsure of what to do next. Do I need to install software first, dig into the BIOS (or the like?) 

Thanks for the help, I've done as much research as I can but I figured now was a good time to check in.