2016 13" MacBook Pro [6th,2C,U] + RX 480 @ 32Gbps-TB3 (AKiTiO Thunder3) + macOS 10.12.2 [ikir]  

Received my MacBook 2016 yesterday (it is my dream machine!!!) I will update this thread with my experience  building an eGPU with Thunder3

 My configuration:

MacBook Pro 13" touchbar, i5 2,9Ghz, 8GB RAM, 512GB SSD, Iris 550

Thunder3 modded with Radeon RX480 4GB connected to LG Ultrawide 4K display

Hardware Installation

1. Opened Thunder3 classic (i will need some time to build an enclosure)

2. Put RX480 in place

3. Connected Thunder3 to DA-2 PSU with a modded cable which power both RX480 (8-pin PCie) and Akitio Thunder3 (barrel plug)

 4. Connect to Mac

macOS configuration

1. Disabled SIP with csrutil from Recovery terminal

2. Downloaded TB3 enabler to let MacBook Pro use Thunder3 (sadly if you don't want to edit kext there is no way yet since Apple software blocked older Thunderbolt 3 devices)

3. Run new automate-GPU script for macOS 10.12.2+ (coming soon)

4. Optional run script for unlocking all Baffin  units to boooooooost OpenCL

 Preliminary benchmarks:

I get OpenGL, OpenCL and Metal acceleration, the gfx card is super silent and very fast (and cheap too). There are still issue but i didn't got any artifact connecting it directly to Thunderbolt3.

 Valley Benchmark 4K 3440x1440 ultrawide 2x ultra:

Iris 550 5fps - 207 score

Thunder3+RX 480 23.4fps - 980 score

 Geekbench 4 GPU:

Iris 550 30584 OpenCL score

Thunder3+RX 480 (with baffin script) 107071 OpenCL score

Luxmark luxball:

Thunder3+RX 480 (with baffin script) 14222

Thunder3+RX 480 (with baffin script) + Iris 550 15423

Cinebench R15 OpenGL:

Thunder3+RX 480 68,70 fps

UPDATE: there are issues with TB3 connection and Radeon cards, so for now i discourage anyone to build this setup. I was able to boot after many many tries. I switched to Nvidia GTX 780ti and it runs fasteeer and boots most of  time.

https://egpu.io/forums/builds/late-2016-13-mbp-gtx780-ti32gbps-tb3-akitio-thunder3-macos-10-12-3-ikir/